An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization
作者： Jens Meiler , Cecilia M. Canessa , Cecilia M. Canessa , Georg Kuenze , Zhuyuan Chen
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摘要: … Rosetta calculations of free energy changes predict that substitutions of R64 in hASIC1a by aromatic residues destabilize the closed conformation while stabilizing the open …
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