Solubility of Fullerenes in Fatty Acids Esters: A New Way to Deliver In Vivo Fullerenes. Theoretical Calculations and Experimental Results

作者: Franco Cataldo

DOI: 10.1007/978-1-4020-6845-4_13

关键词:

摘要: The biological effects of fullerenes and, in particular, C60 have been recognized since long time. One the problems which hindered application medicinal chemistry regards their insolubility water and water-based fluids. In present chapter it is reported that C70 are soluble vegetable oils, general, esters fatty acids free acids. These results pave way utilization oils as vehicles delivery for both topical applications internal use (e.g., intramuscular injection).

参考文章(33)
R. S. Ruoff, Doris S. Tse, Ripudaman Malhotra, Donald C. Lorents, Solubility of fullerene (C60) in a variety of solvents The Journal of Physical Chemistry. ,vol. 97, pp. 3379- 3383 ,(1993) , 10.1021/J100115A049
Dietmar P. Berger, Rupert Engelhardt, Hartmut Henß, Jürgen Scheele, Claudia I. Müller, Alexandra Göbel, Beate Lubrich, Anna-Katharina Kaskel, Hendrik Veelken, Karin Potthoff, Ralph Waesch, Uwe Martens, Claudia Schmoor, Herbert Maier-Lenz, Antonia Müller, Pharmacology and Pharmacotherapy Springer, Berlin, Heidelberg. pp. 65- 203 ,(2008) , 10.1007/978-3-540-73277-8_3
Rodney S. Ruoff, Karl M. Kadish, Fullerenes : chemistry, physics, and technology Wiley-Interscience. ,(2000)
Joel Henry Hildebrand, Robert L. Scott, The solubility of non-electrolytes Reinhold. ,(1936)
N. Sivaraman, R. Dhamodaran, I. Kaliappan, T. G. Srinivasan, P. R. P. Vasudeva Rao, C. K. C. Mathews, Solubility of C70 in Organic Solvents Fullerenes Nanotubes and Carbon Nanostructures. ,vol. 2, pp. 233- 246 ,(1994) , 10.1080/15363839408009549
Tibor Braun, László Márk, Róbert Ohmacht, Uma Sharma, None, Olive Oil as a Biocompatible Solvent for Pristine C60 Fullerenes Nanotubes and Carbon Nanostructures. ,vol. 15, pp. 311- 314 ,(2007) , 10.1080/15363830701423914