Complete covalent structure of human beta-thromboglobulin.
作者： Geoffrey S. Begg , Duncan S. Pepper , Colin N. Chesterman , Francis J. Morgan
DOI: 10.1021/BI00602A024
关键词:
摘要: The complete primary structure of the platelet-specific protein human beta-thromboglobulin has been determined. beta-Thromboglobulin consists identical subunits 81 amino acids, each with a molecular weight 8851. acid sequence subunit is: Gly-Lys-Glu-Glu-Ser-Leu-Asp-Ser-Asp-Leu-Tyr-Ala-Glu-Leu-Arg-Cys-Met-Cys-Ile-Lys-Thr-Thr-Ser-Gly-Ile-His-Pro-Lys-Asn-Ile-Gln-Ser-Leu-Glu-Val-Ile-Gly-Lys-Gly-Thr-His-Cys-Asn-Gln-Val-Glu-Val-Ile-Ala-Thr-Leu-Lys-Asp-Gly-Arg-Lys-Ile-Cys-Leu-Asp-Pro-Asp-Ala-Pro-Arg-Ile-Lys-Lys-Ile-Val-Gln-Lys-Lys-Leu-Ala-Gly-Asp-Glu-Ser-Ala-Asp. Disulfide bridge-18 to half-cystine-58. shows marked homology that platelet factor 4. When sequences are aligned for maximum homology, 42 residues those 4, including position four half-cystines.
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