Development, testing, and findings of a pediatric-focused trigger tool to identify medication-related harm in US children's hospitals.

摘要: OBJECTIVES. The purposes of this study were to develop a pediatric-focused tool for adverse drug event detection and describe the incidence characteristics events in children’s hospitals identified by tool. METHODS. A pediatric-specific trigger was developed tested. Eighty patients from each site randomly selected retrospective chart review. All using evaluated severity, preventability, ability mitigate, identify earlier, presence associated occurrence report. Each entire positive predictive value. RESULTS. Review 960 charts 12 revealed 2388 triggers (2.49 per patient) 107 unique events. Mean rates 11.1 100 patients, 15.7 1000 patient-days, 1.23 medication doses. value 3.7%. Twenty-two percent all deemed preventable, 17.8% could have been 16.8% mitigated more effectively. Ninety-seven resulted mild, temporary harm. Only 3.7% existing hospital-based reports. most common pruritis nausea, classes causing opioid analgesics antibiotics, stages management process with preventable monitoring prescribing/ordering. CONCLUSIONS. Adverse hospitalized children are substantially higher than previously described. Most harm, 22% classified as preventable. traditional voluntary reporting methods. Our is effective at identifying inpatient pediatric populations.