作者: Cheryl G. Bolinger , Rutul R. Shah , Thomas D. Reed
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摘要: Disclosed herein are polynucleotides encoding ligand-inducible gene switch polypeptides, and systems comprising polypeptides for modulating the expression of a heterologous an interleukin in host cell. The compositions, methods described facilitate ligand dependent including but not limited to cytokines antigen binding polypeptides.