Hypusine Biosynthesis in Protein and its Biological Consequences
作者： Roberta J. Murphey , Margaret E. Tome , Eugene W. Gerner
DOI: 10.1007/978-1-4684-5637-0_39
关键词:
摘要: In 1971, the amino acid known as hypusine was discovered in free form bovine brain (Shiba et al., 1972). The structure of established and confirmed N6-(4-amino-2-hydroxybutyl)-2, 6-diamino hexanoic 1982; Tice Ganem, 1983). Since its discovery, has been found a (Nakajima 1971) bound to protein (Sano 1984). Protein-bound primarily occurred protein, M ≃ 18, 000, which originally observed lectin-stimulated lymphocytes Chinese hamster ovary (CHO) cells (Park 1981; Cooper al, 1982). synthesis protein-bound coincides with an increase (Cooper 1982) this biochemical process several mammalian cell lines (Chen, 1983; Torrelio Because ubiquity modification Mr 000 conservation among eukaryotes (Paric 1984a; Gordon 1987), biophysical characteristics were compared those eukaryotic translation initiation factors. MΓ modified by identified putative factor eIF-4D
springer.com
elsevier.com
sci-hub.st 参考文章(34)
Herbert L. Cooper, Myung Hee Park, J.E. Folk, Posttranslational formation of hypusine in a single major protein occurs generally in growing cells and is associated with activation of lymphocyte growth Cell. ,vol. 29, pp. 791- 797 ,(1982) , 10.1016/0092-8674(82)90441-X
Bruce Ganem, New chemistry of naturally occurring polyamines Accounts of Chemical Research. ,vol. 14, pp. 290- 298 ,(1982) , 10.1021/AR00081A004
Kuang Yu Chen, An 18 000-dalton protein metabolically labeled by polyamines in various mammalian cell lines Biochimica et Biophysica Acta. ,vol. 756, pp. 395- 402 ,(1983) , 10.1016/0304-4165(83)90350-1
Kuang Yu Chen, Qing Ping Dou, NAD+
stimulated the spermidine-dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells FEBS Letters. ,vol. 229, pp. 325- 328 ,(1988) , 10.1016/0014-5793(88)81149-9
Colin M. Tice, Bruce Ganem, Chemistry of naturally occurring polyamines. 7. Selective functionalization of hydroxyputrescine Journal of Organic Chemistry. ,vol. 48, pp. 5043- 5048 ,(1983) , 10.1021/JO00173A049
B.Marina Torrelio, Mercedes A. Paz, Paul M. Gallop, Cellular proliferation and hypusine synthesis Experimental Cell Research. ,vol. 154, pp. 454- 463 ,(1984) , 10.1016/0014-4827(84)90169-1
Akira Sano, Masaharu Miyake, Yasuo Kakimoto, A rapid and sensitive method for the determination of hypusine in proteins and its distribution and developmental changes. Biochimica et Biophysica Acta. ,vol. 800, pp. 135- 139 ,(1984) , 10.1016/0304-4165(84)90051-5
Pierre S. Mamont, Marie-Christine Duchesne, Jeffrey Grove, Philippe Bey, Anti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase Biochemical and Biophysical Research Communications. ,vol. 81, pp. 58- 66 ,(1978) , 10.1016/0006-291X(78)91630-3
A.P. Campello, C.W. Tabor, H. Tabor, Resolution of spermidine dehydrogenase from Serratiamarcescens: Requirements for flavin adenine dinucleotide and an additional electron carrier Biochemical and Biophysical Research Communications. ,vol. 19, pp. 6- 9 ,(1965) , 10.1016/0006-291X(65)90109-9
A.A.M Thomas, R. Benne, H.O. Voorma, INITIATION OF EUKARYOTIC PROTEIN SYNTHESIS FEBS Letters. ,vol. 128, pp. 177- 185 ,(1981) , 10.1016/0014-5793(81)80076-2