Advances and Barriers for Clinical Neuroimaging in Late-Life Mood and Anxiety Disorders

摘要: Mood and anxiety disorders are very commonly experienced by older adults becoming a growing concern due to the rapidly aging global population. Recent advances in neuroimaging may help improving outcomes late-life mood disorders. The elucidation of mechanisms contributing mental health ultimately lead identification novel therapeutic interventions. Alternatively, clinically validated imaging biomarkers allow for prediction treatment response better approaches In community samples, depression generalized disorder occur up 38 15%, respectively, while bipolar is less common approximately 0.5% There significant challenges treating outcome Time resistance increased adults. Novel techniques have potential improve diagnostic either through “personalized pharmacotherapy” or identifying dysfunction regions/networks be subsequently used direct interventions such as transcranial magnetic stimulation. This review will provide an overview recent literature that substantiates role clinical practice, well barriers must overcome prior translation.