Impact of pulmonary hypertension on transplant outcomes in pediatric cardiomyopathy patients
作者： Sujatha Buddhe , Wei Du , Thomas L’Ecuyer
DOI: 10.1111/J.1399-3046.2012.01678.X
关键词:
摘要: Controversy exists over whether PHTN in heart transplant candidates increases post-transplant mortality. We performed analysis of data reported to UNOS for children who underwent primary transplantation cardiomyopathy from January 1994 June 2010. Patients were divided into two groups depending on their pre-transplant TPG: no-PHTN (TPG £ 12 mmHg) and >12 mm Hg). A total 6139 whom 2456 (40%) cardiomyopathies; 1322 (54%) these had catheteri- zation available. The group (mean TPG 19.5 ± 8.6) 312 patients 6.7 4.0) 1010. Mortality at one month (4.5% vs. 2.3%) three months (6.1% 3.1%) post- was significantly higher the than with an odds ratio 2 (p < 0.05). There no significant effect early mortality <1 yr age. sig- nificant improvement survival transplants after compared before 2003 despite availability pulmonary dilators. Pre-transplant post-trans- plant pediatric above has been outcome this last seven yr.
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sci-hub.se 参考文章(30)
M J Zucker, M R Johnson, J A Robinson, P J Scanlon, E J O'Sullivan, K W Erickson, R Pifarré, M R Costanzo-Nordin, C E Lawless, Influence of preoperative transpulmonary gradient on late mortality after orthotopic heart transplantation. The Journal of heart transplantation. ,vol. 9, pp. 526- 537 ,(1990)
P. Vouhe, W. Khoury, P. Mauriat, J. Le Bidois, D. Tamisier, F. Leca, Donor-recipient size matching in pediatric heart transplantation : A word of caution about small grafts Journal of Heart and Lung Transplantation. ,vol. 15, pp. 190- 195 ,(1996)
Stuettgen B, Mirow N, Tenderich G, Arusoglu L, Morshuis M, Koerner Mm, Minami K, Koerfer R, Bairaktaris A, Pre-existing elevated pulmonary vascular resistance: long-term hemodynamic follow-up and outcome of recipients after orthotopic heart transplantation. Journal of Cardiovascular Surgery. ,vol. 41, pp. 215- ,(2000)
Norihide Fukushima, Steven R. Gundry, Anees J. Razzouk, Leonard L. Bailey, Risk factors for graft failure associated with pulmonary hypertension after pediatric heart transplantation. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 107, pp. 985- 989 ,(1994) , 10.1016/S0022-5223(94)70372-8
Stefan Klotz, Frauke Wenzelburger, Joerg Stypmann, Henryk Welp, Gabriele Drees, Christof Schmid, Hans H. Scheld, Reversible Pulmonary Hypertension in Heart Transplant Candidates: To Transplant or Not to Transplant The Annals of Thoracic Surgery. ,vol. 82, pp. 1770- 1773 ,(2006) , 10.1016/J.ATHORACSUR.2006.05.114
Ranjit John, Hiranya Rajasinghe, Jonathan M. Chen, Alan D. Weinberg, Prashant Sinha, Silviu Itescu, Katherine Lietz, Donna Mancini, Mehmet C. Oz, Craig R. Smith, Eric A. Rose, Niloo M. Edwards, Impact of Current Management Practices on Early and Late Death in More Than 500 Consecutive Cardiac Transplant Recipients Annals of Surgery. ,vol. 232, pp. 302- 311 ,(2000) , 10.1097/00000658-200009000-00002
Jonathan M. Chen, Howard R. Levin, Robert E. Michler, Chad J. Prusmack, Eric A. Rose, Keith D. Aaronson, Reevaluating the significance of pulmonary hypertension before cardiac transplantation: determination of optimal thresholds and quantification of the effect of reversibility on perioperative mortality. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 114, pp. 627- 634 ,(1997) , 10.1016/S0022-5223(97)70053-9
Michael Gorlitzer, Jan Ankersmit, Nikolaus Fiegl, Johann Meinhart, Michaela Lanzenberger, Keziban Unal, Daniela Dunkler, Juliane Kilo, Ernst Wolner, Michael Grimm, Martin Grabenwoeger, Is the transpulmonary pressure gradient a predictor for mortality after orthotopic cardiac transplantation Transplant International. ,vol. 18, pp. 390- 395 ,(2005) , 10.1111/J.1432-2277.2004.00038.X
James F McCarthy, Patrick M McCarthy, Malek G Massad, Daniel J Cook, Nicholas G Smedira, Vigneshwar Kasirajan, Marlene Goormastic, Kathy Hoercher, James B Young, Risk Factors for Death After Heart Transplantation: Does a Single-Center Experience Correlate With Multicenter Registries? The Annals of Thoracic Surgery. ,vol. 65, pp. 1574- 1578 ,(1998) , 10.1016/S0003-4975(98)00138-6
Stavros G. Drakos, Abdallah G. Kfoury, Edward M. Gilbert, Benjamin D. Horne, James W. Long, James C. Stringham, Beverly A. Campbell, Dale G. Renlund, Effect of reversible pulmonary hypertension on outcomes after heart transplantation Journal of Heart and Lung Transplantation. ,vol. 26, pp. 319- 323 ,(2007) , 10.1016/J.HEALUN.2007.01.012