Pathogenesis of Biomaterial-Associated Infection
作者： S. T. Jerry Tsang , A. Hamish R. W. Simpson
DOI: 10.1007/978-3-030-34475-7_6
关键词:
摘要: Biomaterial infections associated with indwelling surgical devices are responsible for ~50% of all nosocomial infections. The development orthopedic biomaterial-associated comes at great physical and emotional cost to patients, resulting in substantial economic costs healthcare providers. Understanding its pathogenesis has progressed greatly since the biofilm hypothesis was first proposed. However, only partially elucidates these A greater appreciation mechanisms underpinning immune evasion by common pathogens highlighted a previous underestimation role this behavior troublesome Recognition importance system interaction will not update our paradigm condition but also help identify develop potential therapeutic targets. This review aims provide an overview It focuses primarily on bacterial biofilms immune-evasive most pathogens.
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