Leukocyte migration inhibitory factor in HSV infections.

作者: Y M Centifanto , H E Kaufman , J I McNeill , Z S Zam

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摘要: The cell-mediated immune (CMI) response as measured by a direct assay of leukocyte migration inhibition factor (LMIF) was determined in population patients with recurrent herpes simplex virus (HSV) infections the quiescent stage well healthy volunteers. leukocytes incubated presence HSV antigens compared to that without viral for calculation index (MI). Eleven 41 control subjects (16.8%) had MI below 0.8, indicating positive CMI response. In contrast, all tested above suggesting an impairment production LMIF at this their disease. This difference statistically significant (t = 4.296; p less than 0.001) and not dependent on age population. study indicates individuals have impaired betweeen attacks which may be associated

参考文章(1)
M. L. Cook, V. B. Bastone, J. G. Stevens, Evidence that Neurons Harbor Latent Herpes Simplex Virus Infection and Immunity. ,vol. 9, pp. 946- 951 ,(1974) , 10.1128/IAI.9.5.946-951.1974