A Clinical Trial with Combined Transcranial Direct Current Stimulation and Attentional Bias Modification in Alcohol‐Dependent Patients

摘要: Modifying attentional processes with bias modification (ABM) might be a relevant add-on to treatment in addiction. This study investigated whether influencing cortical plasticity transcranial direct current stimulation (tDCS) could increase training effects. tDCS also help alcohol-dependent patients overcome craving and reduce relapse, independent of training. These approaches were combined investigate effects the alcoholism. Ninety-eight (analytical sample = 83) randomly assigned 4 groups 2-by-2 factorial design. Patients received sessions ABM (control or real training) 2 mA (active: 20 minutes sham: 30 seconds) over left dorsolateral prefrontal cortex. Alcohol assessed, outcome was measured as relapse after 1 year. Attentional scores indicated that during only group active displayed an overall avoidance (p   0.2). However, on expected direction. There no evidence beneficial effect combination. Whether absence due issues measurements (e.g., lack craving, high dropout, unreliable measurements) aspects intervention should further investigated. [Abstract copyright: © 2018 The Authors Alcoholism: Clinical & Experimental Research published by Wiley Periodicals, Inc. behalf Society Alcoholism.]