Congenital heart disease and brain development

摘要: Brain and heart development occur simultaneously in the human fetus. Given depth complexity of these shared morphogenetic programs, it is perhaps not surprising that disruption organogenesis one organ will impact other. Newborns with congenital disease show a high frequency acquired focal brain injury on sensitive magnetic resonance imaging studies perioperative period. The surprisingly incidence white matter term newborns suggests unique vulnerability may be related to delay development. These abnormalities identified MRI might reflect cerebral blood flow while utero. A complete understanding mechanisms newborn require further investigation timing, extent, causes delayed fetal presence disease.