Novel heart diseases requiring transplantation.

摘要: Cardiac transplantation represents an extraordinary opportunity to study in vivo the pathology of native disease terminal phase. The experience cumulated at University Padua 418 orthotopic cardiac transplant procedures allowed come across previously unrecognized disease: idiopathic left ventricular aneurysm, non-compacted (spongy) myocardium, restrictive cardiomyopathy. A discrepancy between pre- and post-transplant diagnosis was found 8% cases. Endomyocardial biopsy coronary arteriography should be carried out each patient with apparently dilated cardiomyopathy before proceeding heart removal, since alternative therapeutic may available.