Severe pulmonary oedema following therapeutic embolization with Onyx for cerebral arteriovenous malformation

摘要: Acute respiratory distress syndrome (ARDS) is characterized by sudden onset of distress, infiltrates on radiographs consistent with pulmonary oedema, hypoxaemia and increased work in breathing. Infiltrates are bilateral, but may be patchy or diffuse fluffy dense. It associated absence left heart failure a PaO2/FiO2 ratio < =200. Ethylene vinyl alcohol copolymer dissolved dimethyl sulfoxide (DMSO), which was approved the US FDA July 2005, used as an embolic agent for cerebral arteriovenous malformation (AVM). biocompatible liquid polymer that precipitates solidifies contact blood, thus forming soft spongy embolus. We report case ARDS following therapeutic embolization ethylene AVM under general anaesthesia. Experienced perioperative physicians adopted standard anaesthetic technique monitoring this procedure. developed patient extubation trachea. seen postprocedural chest were oedema. DMSO, solvent copolymer, excreted via lungs after administration we postulate DMSO possible cause patient. Monitoring haemodynamic parameters (invasive blood pressure, electrocardiography) ventilatory (ETCO2, SpO2, airway pressure monitoring) important recognition event. One should vigilant anticipate complication treatment AVM.