Infección por Clostridium difficile
作者： Roberto Chiprut , Elena Cortés-Nava , M. Alejandro Castellanos-Urdaibay , Mónica Ivonne Portillo-López
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摘要: El Clostridium difficile es un bacilo anaerobio formador de esporas subterminales grandes, forma oval, localizadas en el intestino. Posee dos enterotoxinas que producen amplios danos las celulas del intestino y asi ocasionar diarrea. Los pacientes pueden presentar amplio espectro la enfermedad, va diarrea simple no complicada asociada al uso antibioticos, hasta colitis seudomembranosa estos, potencialmente mortal. C. Difficile tiene serotipos. Existen cepas patogenas patogenas. Las ultimas cantidades variables toxina A (enterotoxina) B (citotoxina). tratamientos con antibioticos eliminan gran cantidad flora normal, permitiendo sobrecrecimiento patogeno. No existen defensas inmunologicas definidas huesped. tratamiento puede basarse metronidazol o vancomicina, aunque suelen ocurrir recidivas. Puede requerirse apoyo. Palabras clave: difficile, seudo-membranosa, cronica
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