作者: Corrigan Tp , Fossard Dp , Sutherland I , Thirwell J , Kakkar Vv
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摘要: The results of a multicentre trial, designed to assess the efficacy low-dose heparin in preventing fatal postoperative pulmonary embolism, were published July 1975. In view inconsistencies which have now become apparent data from one twenty-eight centres took part trial been re-examined, excluding this centre. Of 4031 patients remaining after exclusion these data, 2033 control group and 1998 group. 170 (4-2%) died during period, 94 76 group; 70-2% deaths 65-7% had necropsy examination. 15 none found at due acute massive embolism (P less than 0-001). Exclusion centre did not alter already significant differences total incidence deep-vein thrombosis, nor frequency operative post-operative bleeding complications observed