A simulation study on power comparisons for group sequential tests of non-parametric statistics

作者: Y. Parlak Demirhan , H. Demirhan , S. Bacanli

DOI: 10.1080/00949650801930682

关键词:

摘要: In this article, a group sequential test (GST) of non-parametric statistics for survival data is briefly reviewed. An asymptotic joint distribution the statistics, obtained after each interim analysis, given to illustrate applicability critical values GST procedures. It should be noted that censored observations are generally seen in data. Therefore, if one makes power calculations irrespective censoring, reliable results may not achieved, due lack information about censoring structure. A wide simulation study, covering different rates and tied observations, conducted make comparisons under various scenarios. The interpreted compared with by using analysis sample size (PASS) software.

参考文章(18)
Bruce W. Turnbull, Christopher Jennison, Group Sequential Methods with Applications to Clinical Trials ,(1999)
THIERRY MOREAU, JEAN MACCARIO, JOSEPH LELLOUCH, CATHERINE HUBER, Weighted log rank statistics for comparing two distributions Biometrika. ,vol. 79, pp. 195- 198 ,(1992) , 10.1093/BIOMET/79.1.195
K. K. GORDON LAN, DAVID L. DEMETS, Discrete sequential boundaries for clinical trials Biometrika. ,vol. 70, pp. 659- 663 ,(1983) , 10.1093/BIOMET/70.3.659
Eric Slud, L. J. Wei, Two-Sample Repeated Significance Tests Based on the Modified Wilcoxon Statistic Journal of the American Statistical Association. ,vol. 77, pp. 862- 868 ,(1982) , 10.1080/01621459.1982.10477899
Anastasios A. Tsiatis, Repeated Significance Testing for a General Class of Statistics Used in Censored Survival Analysis Journal of the American Statistical Association. ,vol. 77, pp. 855- 861 ,(1982) , 10.1080/01621459.1982.10477898
Peter C. O'Brien, Thomas R. Fleming, A multiple testing procedure for clinical trials. Biometrics. ,vol. 35, pp. 549- 556 ,(1979) , 10.2307/2530245
Sandro Pampallona, Anastasios A. Tsiatis, Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis Journal of Statistical Planning and Inference. ,vol. 42, pp. 19- 35 ,(1994) , 10.1016/0378-3758(94)90187-2