A Comparative Mechanistic and Kinetic Study of the Synthesis Reaction of 3, 4, 5‐Substituted Furan‐2(5H)‐ones: Solvent Effect
作者： Sayyed Mostafa Habibi-Khorassani , Mehdi Shahraki , Maryam Dehdab
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摘要: Solvent can influence kinetics and mechanism of a chemical reaction. Herein, the different behavior solvent media on competitive between benzaldehyde (1), 4-ethylaniline (2) diethyl acetylenedicarboxylate (3) has been described when was changed from acidic pH range (formic acid in previous work) to values near or above neutrality (ethanol recent work). Experimental documents obtained using UV-vis stopped-flow spectrophotometry techniques. The results showed that reaction presence ethanol followed second order with respect (1) (2), while it work acid) relation (3). A speculative involving five steps proposed first step encountered largest energy barrier as rate-determining (RDS). Furthermore, influences temperature concentration rate were investigated. Activation parameters (ΔH≠ , ΔS≠ ΔG≠ ) along (kove Ea) determined. entropy controlled solvent.
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