Hypothalamic control of anterior pituitary hormone secretion--characterized hypothalamic-hypophysiotropic peptides.
作者： Geoffrey F. Grant , Wylie Vale
DOI: 10.1016/B978-0-12-153202-4.50008-X
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摘要: Publisher Summary The central nervous system has a directing role over the anterior pituitary–peripheral hormone system. hypothalamus controls pituitary functions by means of peptide hormones secreted, on signal, into portal blood that connects them. peptides either stimulate or inhibit release stored hormone, apparently, via their interaction with extracellular membrane receptors. Five hypothalamic extract activities have been reported to isolated and chemically synthesized. chapter discusses various identified releasing factors respect effects upon pituitary, structure activity relationships each, interrelation feedback control exhibited peripheral endocrine hormones. Hypothalamic regulating secretion expanded dramatically in past few years. clinical experimentation application physiological pathological conditions is only its infancy but shows satisfying promise.
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