Life events and alcohol use disorder clinical course: Modeling the dynamic association.

摘要: Abstract Background Despite over 35 years of study, the relationship between life events (LEs) and alcohol use disorder (AUD) treatment outcome lacks consistent empirical support, which may be due to a lack theoretically driven designs corresponding statistical analyses. The purpose this study was elucidate LEs-AUD by statistically modeling dynamic negative LEs post-treatment, as it is conceptualized within model relapse. Methods Existing longitudinal data from 417 AUD treatment-seeking adults were randomly assigned two demographically comparable samples. One sample ( N  = 208) used estimate series bivariate latent change score models that differentially relate indicators distal proximal (i.e., subjectively rated negative) percent heavy drinking days across 12 months. Cross-validation conducted on second  = 209). Results Findings indicated positively associated with greater increase in LEs, but not drinking, subsequent Proximal significantly increases though determinant LEs. These findings cross-validated sample. Conclusions This provides initial justification for further LEs-alcohol described