Influence of Contact Time and Concentration of Chlorhexidine Varnish on Mutans Streptococci in Interproximal Dental Plaque

摘要: This study describes the effects of varnishes containing 0, 25, 33 and 40% chlorhexidine diacetate on mutans streptococci in human approximal dental plaque. The release from was determined vitro. Eleven subjects participated clinical experiment, each with at least five areas harboring high levels streptococci. individuals were randomly assigned to experimental groups, which one tested; varnish tested two groups. treatment consisted a single application small amount onto selected areas. From sites receiving varnish, all visible removed 15 min after application. volunteers asked leave remaining treated not brush their teeth for 8 h. All strongly suppressed until 4 months extent suppression depended upon concentration giving greatest No significant difference found between numbers where left. results suggested that can be used successfully long-term A contact time tooth surface only is sufficient achieve this suppression.