1,3-Dipolar cycloadditions of nitrones to α,β-unsaturated γ-lactams derived from (S)-pyroglutaminol

作者: Nicole Langlois , Nguyen Van Bac , Nathalie Dahuron , Jean-Marc Delcroix , Abdallah Deyine

DOI: 10.1016/0040-4020(95)00100-M

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摘要: Abstract α,β-Unsaturated γ-lactams undergo regio- and stereoselective 1,3-dipolar cycloadditions with N-benzyl N-methyl nitrones can act as acceptors in conjugate addition of N-methylhydroxylamine. These reactions give access to highly functionalized pyrrolidones.

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