Non-peptide bradykinin receptor antagonists for use in controlling intraocular pressure and treating glaucoma

Ester Tobias, Josep M. Nicolas, Rafael Barraquer, Artur Llobet, Jordi Pales, Arcacli Gual, Bradykinin decreases outflow facility in perfused anterior segments and induces shape changes in passaged BTM cells in vitro Investigative Ophthalmology & Visual Science. ,vol. 40, pp. 113- 125 ,(1999)

M J Berridge, C P Downes, M R Hanley, Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands Biochemical Journal. ,vol. 206, pp. 587- 595 ,(1982) , 10.1042/BJ2060587

Brent D. Douty, Joseph M. Salvino, Peter R. Seoane, Roland E. Dolle, Synthesis of non-peptide bradykinin B2 receptor antagonists Bioorganic & Medicinal Chemistry Letters. ,vol. 5, pp. 363- 366 ,(1995) , 10.1016/0960-894X(95)00036-S

Melanie Hingorani, Susan Lightman, Therapeutic options in ocular allergic disease. Drugs. ,vol. 50, pp. 208- 221 ,(1995) , 10.2165/00003495-199550020-00002

J.N. Sharma, Therapeutic prospects of bradykinin receptor antagonists General Pharmacology: The Vascular System. ,vol. 24, pp. 267- 274 ,(1993) , 10.1016/0306-3623(93)90302-E

Ved P. Srivastava, Val S. Goodfellow, John S. Zuzack, Steve Jones, Mary Francis, Virginia E. Beckey, Eric T. Whalley, Hybrid peptides having mixed substance P (NK1), neurokinin A (NK2) and bradykinin (BK2) antagonist properties. Immunopharmacology. ,vol. 33, pp. 194- 197 ,(1996) , 10.1016/0162-3109(96)00038-0

N.A. SHARIF, S.X. XU, Pharmacological characterization of bradykinin receptors coupled to phosphoinositide turnover in SV40-immortalized human trabecular meshwork cells. Experimental Eye Research. ,vol. 63, pp. 631- 637 ,(1996) , 10.1006/EXER.1996.0157

Judith M. Hall, Michela Figini, Semal K. Butt, Pierangelo Geppetti, Inhibition of bradykinin-evoked trigeminal nerve stimulation by the non-peptide bradykinin B2 receptor antagonist WIN 64338 in vivo and in vitro. British Journal of Pharmacology. ,vol. 116, pp. 3164- 3168 ,(1995) , 10.1111/J.1476-5381.1995.TB15119.X

N SHARIF, R WHITING, Identification of B2-bradykinin receptors in guinea pig brain regions, spinal cord and peripheral tissues Neurochemistry International. ,vol. 18, pp. 89- 96 ,(1991) , 10.1016/0197-0186(91)90041-B

Paul L. Kaufman, Ernst H. Bárány, Kristine A. Erickson, Effect of serotonin, histamine and bradykinin on outflow facility following ciliary muscle retrodisplacement in the cynomolgus monkey Experimental Eye Research. ,vol. 35, pp. 191- 199 ,(1982) , 10.1016/S0014-4835(82)80066-3