Cognitive manipulation of brain electric microstates.

摘要: EEG studies of wakeful rest have shown that there are brief periods in which global electrical brain activity on the scalp remains semi-stable (so-called microstates). Topographical analyses this revealed much variance is explained by four distinct microstates occur a repetitive sequence. A recent fMRI study showed these correlated with known functional systems, each activated specific cognitive functions and sensory inputs. The present used high density to examine degree spatial temporal properties may be altered manipulating task (a serial subtraction vs. rest) availability visual information (eyes open eyes closed conditions). hypothesis was parameters microstate D would during because it regions part dorsal attention system. It also expected sequence preferentially transition from all other as compared rest. Finally, hypothesized condition significantly increase one or more associated B, indicated duration, coverage, occurrence were higher rest; addition, C, default mode control very sensitive manipulation, showing decreased Moreover, B manipulations input, increased coverage condition. In had shorter durations, while C occurrence. Microstate at least 15 (identified via k-means clustering) required explain similar amount previously published values. These results support important aspects our hypotheses demonstrate manipulation possible, but relationships between their corresponding systems complex. than primary microstates.