Regional Arterial Therapy in the Management of Primary Liver Neoplasms

摘要: Survival of untreated patients with inoperable primary liver neoplasms is approximately 75 days [1,2]. Before doxorubicin, both intravenous and intra-arterial chemotherapeutic agents had very little effect upon the survival these despite tumor shrinkage [3,4]. An early report given intravenously as a single agent or in combination other drugs, resulted response 78% [5]. Later studies reported rates ranging from 9% to 44% [6–14]. In 67% neoplasms, disease seems confined at time diagnosis, even autopsy still [15]. A regional approach such dismal prognosis warranted. pilot study hepatic arterial infusion floxuridine, mitomycin C (FUDRAM) rate 66% hepatocellular carcinoma [16]. We decided, therefore, explore this treatment regimen further, chapter we describe our experience discuss possible role intrahepatic artery chemotherapy cancer.