Amino-acid Substitutions in Haemoglobins and the Mutation Process
作者： F. VOGEL , G. RÖHRBORN
DOI: 10.1038/210116A0
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摘要: VARIOUS genetically determined human and animal haemoglobins differ in the amino-acid sequences of their polypeptide chains1,3,6. On basis ribonucleic acid triplets published recently4,5 all abnormal which are due to single substitutions can be explained by base pair changes deoxyribonucleic acid. Comparing normal β- δ-chains we found that only exchange threonine glutamine position 87 (1 10) cannot interpreted a point mutation.
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