UT-DSAEK avec greffons préparés en banque, suivi de 79 greffes sur un an

作者: V. Bielefeld , B. Vabres , M. Baud’huin , P. Lebranchu , G. Le Meur

DOI: 10.1016/J.JFO.2020.04.060

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摘要: Resume Introduction L’UT-DSAEK est une technique recente qui permet d’obtenir des greffons plus fins qu’une DSAEK classique, soit inferieurs a 100 microns. L’objectif de cette etude d’etudier les resultats anatomocliniques sur duree d’un an serie retrospective d’UT-DSAEK au CHU Nantes, utilisant prealablement predecoupes en banque tissus et comparer ces aux autres techniques existantes, savoir la DMEK. Materiel methode Dans monocentrique etaient inclus tous patients necessitant greffe endotheliale an. Les criteres etudies etaient l’acuite visuelle, l’epaisseur du greffon, pachymetrie microscopie speculaires, recueillies visites preoperatoires, J7, M1, M3, M6 et M12. Resultats Soixante-dix-neuf greffes ont ete realisees chez 75 patients. L’âge moyen etait 72 ans. Entre le 7e jour fin premiere annee, greffon centre l’axe passe 75 ± 29 a 60 ± 21 microns avec cinetique decroissance rapide trois premiers mois. La 706 ± 95 microns preoperatoire 561 ± 54 microns meme decroissance. densite cellulaire 2604  ± 13 cell/mm2 avant 1551  ± 124 cell/mm2 a un an, perte 40 %. L’acuite visuelle 1,16 logMAR. Elle s’ameliore rapidement pour atteindre 0,65 logMAR 1er mois, 0,40 logMAR Conclusion Cette apporte nombreux elements l’evolution UT-DSAEK, diminution correspondant remontee l’acuite periode, bonne survie endotheliale. ouvre nouvelles voies dans l’arsenal therapeutique pathologies endotheliales etant complementaire DMEK indications preoperatoires.

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