The analysis, interpretation, and presentation of quality of life data.

摘要: Abstract All too often in clinical trials the assessment of quality life is seen as a bolt-on study. Consequently insufficient consideration given to its design, collection, analysis and presentation, impact on trial results practice minimal. In many key endpoint, it vital that expertise involved soon possible design. Setting priori hypotheses will focus decisions regarding which questionnaire use, when administer it, sample size required, primary analyses. Nevertheless data are complex, require much skill determining how deal with multi-dimensional longitudinal data, missing. There no agreed standard ways analysing presenting but there guidelines, if followed, add transparency way have been calculated. Understanding treatments on...