Effect on emotional behavior and stress by inhalation of the essential oil from Chamaecyparis obtusa.

摘要: Various effects have been reported in the literature for essential oil from Chamaecyparis obtusa (EOCO), such as antibacterial and antifungal activity. In this study, we examined effect of EOCO on emotional behavior stress-induced biomarkers. Male ICR mice, aged 5 weeks at start each experiment, were individually housed cages 1 week. After placing mouse a glass container exposing it to 90 min, then investigated influence using elevated-plus maze (EPM) test, which is one evaluation methods anxiolytic-like behavior. Significant observed 7.0 mg/L air (P < 0.05). EPM mice dissected changes biomarkers within brain by examining amounts fast nerve growth factor receptor (NGFR) activity regulated cytoskeletal-associated protein (Arc) gene expression, brain-derived neurotrophic (BDNF) galactokinase (GLK1) expression. increases amount NGFR after inhalation These results indicate that has both stress mitigation effects.