Intercalary heterochromatin in Drosophila melanogaster polytene chromosomes and the problem of genetic silencing
作者： Igor F Zhimulev , Elena S Belyaeva , Igor V Makunin , Vincenzo Pirrotta , Valery F Semeshin
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摘要: The morphological characteristics of intercalary heterochromatin (IH) are compared with those other types silenced chromatin in the Drosophila melanogaster genome: pericentric (PH) and regions subject to position effect variegation (PEV). We conclude that IH polytene chromosomes binding sites silencing complexes such as PcG SuUR protein. Binding these proteins results appearance condensed late replication DNA, which turn may result DNA underreplication. PH well PEV have common appearance, localization specific proteins, replication, underreplication chromosomes, ectopic pairing.
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researchgate.net 参考文章(40)
I.F. Zhimulev, Polytene chromosomes, heterochromatin, and position effect variegation. Advances in Genetics. ,vol. 37, pp. 1- 555 ,(1997) , 10.1016/S0065-2660(08)60341-7
Zhimulev If, Volkova Ei, Pirrotta, Makunin, Beliaeva Es, Effect of four doses of the Su(UR)ES gene on intercalary heterochromatin in Drosophila melanogaster Russian Journal of Genetics. ,vol. 36, pp. 1061- 1070 ,(2000)
William K. Baker, Position-effect variegation Advances in Genetics. ,vol. 14, pp. 133- 169 ,(1968) , 10.1016/S0065-2660(08)60426-5
C.S. Chan, L. Rastelli, V. Pirrotta, A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression. The EMBO Journal. ,vol. 13, pp. 2553- 2564 ,(1994) , 10.1002/J.1460-2075.1994.TB06545.X
L. Rastelli, C.S. Chan, V. Pirrotta, Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. The EMBO Journal. ,vol. 12, pp. 1513- 1522 ,(1993) , 10.1002/J.1460-2075.1993.TB05795.X
D. Zink, R. Paro, Drosophila Polycomb-group regulated chromatin inhibits the accessibility of a trans-activator to its target DNA. The EMBO Journal. ,vol. 14, pp. 5660- 5671 ,(1995) , 10.1002/J.1460-2075.1995.TB00253.X
T. D. Kolesnikova, D. E. Koryakov, V. F. Semeshin, E. S. Belyaeva, I. F. Zhimulev, Interlinear Differences in the Morphology of the Pericentric Region of Salivary Gland Polytene X Chromosome ofDrosophila melanogaster Russian Journal of Genetics. ,vol. 37, pp. 1373- 1381 ,(2001) , 10.1023/A:1013239727842
B. Tschiersch, A. Hofmann, V. Krauss, R. Dorn, G. Korge, G. Reuter, The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes. The EMBO Journal. ,vol. 13, pp. 3822- 3831 ,(1994) , 10.1002/J.1460-2075.1994.TB06693.X
Friedrich Back, The Variable Condition of Euchromatin and Heterochromatin International Review of Cytology-a Survey of Cell Biology. ,vol. 45, pp. 25- 64 ,(1976) , 10.1016/S0074-7696(08)60077-7
Lori L Wallrath, Unfolding the mysteries of heterochromatin Current Opinion in Genetics & Development. ,vol. 8, pp. 147- 153 ,(1998) , 10.1016/S0959-437X(98)80135-4