作者: Ikuroh Ohsawa , Masahiro Ishikawa , Kumiko Takahashi , Megumi Watanabe , Kiyomi Nishimaki
DOI: 10.1038/NM1577
关键词:
摘要: Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H2) has potential as an antioxidant in preventive and therapeutic applications. We induced acute oxidative stress in cultured cells by three independent methods. H2 selectively reduced the hydroxyl radical, the most cytotoxic of reactive oxygen species (ROS), and effectively protected cells; …