Analysis of nuclear envelope assembly using extracts of Xenopus eggs.

摘要: Publisher Summary Cell division in the majority of eukaryotes occurs by an open mitosis, which includes, among other processes, disassembly nuclear envelope (NE) as cells prepare to divide, and its reassembly complete karyokinesis. The NEs that reform late mitosis each daughter are assembled from precursors released into cytoplasm when NE dividing cell disassembled. Because new protein synthesis is not required for reassembly, it likely controlled reversible posttranslational modifications, such phosphorylation. best understood changes components during those lamins, major lamina. lamins become highly phosphorylated filaments comprise lamina depolymerize lamin dimers. kinase activity cyclin B/p34 cdc2 complexes thought play a role