Stem cell-derived mitochondria transplantation: A promising therapy for mitochondrial encephalomyopathy.
作者： Kaiming Liu , Mengxiong Pan , Zhijian Zhou , Lining Zhang
DOI: 10.1111/CNS.13618
关键词:
摘要: Mitochondrial encephalomyopathies are disorders caused by mitochondrial and nuclear DNA mutations which affect the nervous muscular systems. Current therapies for inadequate mostly palliative. However, stem cell-derived mitochondria transplantation has been demonstrated to play an key part in metabolic rescue, offers great promise encephalomyopathies. Here, we summarize present status of cell therapy encephalomyopathy discuss transfer routes protection mechanisms cells. We also identify future perspectives challenges treatment these intractable based on concept from
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