Angiogenesis: a potential target for therapy of soft tissue sarcomas

Mats Sjöquist, Carl-Henrik Heldin, Kristofer Rubin, Arne Ostman, Tobias Sjöblom, Elisabeth Buchdunger, Kristian Pietras, Inhibition of PDGF Receptor Signaling in Tumor Stroma Enhances Antitumor Effect of Chemotherapy Cancer Research. ,vol. 62, pp. 5476- 5484 ,(2002)

Luba Roncari, Abhijit Guha, Bodour Salhia, Gerald McMahon, Lilyana Angelov, Inhibition of Angiogenesis by Blocking Activation of the Vascular Endothelial Growth Factor Receptor 2 Leads to Decreased Growth of Neurogenic Sarcomas Cancer Research. ,vol. 59, pp. 5536- 5541 ,(1999)

Raphael E. Pollock, Aiqing Lang, Dihua Yu, Lee M. Ellis, Lianglin Zhang, Mei Hu, Shunbin Xiong, Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression. Cancer Research. ,vol. 60, pp. 3655- 3661 ,(2000)

Thomas Boehm, Judah Folkman, Timothy Browder, Michael S. O'Reilly, Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance Nature. ,vol. 390, pp. 404- 407 ,(1997) , 10.1038/37126

Frederick Eilber, Maggie C. Lee, Sanford H. Barsky, Scott Nelson, James Tomlinson, Samuel Singer, Behnaz Pezeshki, Mai Nguyen, Different patterns of angiogenesis in sarcomas and carcinomas. Clinical Cancer Research. ,vol. 5, pp. 3516- 3522 ,(1999)

B J Dezube, J H Von Roenn, J Holden-Wiltse, T W Cheung, S C Remick, T P Cooley, J Moore, J P Sommadossi, S L Shriver, C W Suckow, P S Gill, Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team. Journal of Clinical Oncology. ,vol. 16, pp. 1444- 1449 ,(1998) , 10.1200/JCO.1998.16.4.1444

Serge Jothy, Guido Bocci, Daniel J. Hicklin, Shan Man, Giulio Francia, Gabriele Bergers, Robert S. Kerbel, Peter Bohlen, Shane K. Green, Douglas Hanahan, Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water. Cancer Research. ,vol. 62, pp. 2731- 2735 ,(2002)

Cecilia Sgadari, Giovanni Barillari, Elena Toschi, Davide Carlei, Ilaria Bacigalupo, Sara Baccarini, Clelia Palladino, Patrizia Leone, Roberto Bugarini, Laura Malavasi, Aurelio Cafaro, Mario Falchi, Donatella Valdembri, Giovanni Rezza, Federico Bussolino, Paolo Monini, Barbara Ensoli, HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma. Nature Medicine. ,vol. 8, pp. 225- 232 ,(2002) , 10.1038/NM0302-225

Nicholas C. Saenz, Martin J. Heslin, Volkan Adsay, Jonathan J. Lewis, Denis H. Leung, Michael P. LaQuaglia, Murray F. Brennan, Neovascularity and clinical outcome in high-grade extremity soft tissue sarcomas. Annals of Surgical Oncology. ,vol. 5, pp. 48- 53 ,(1998) , 10.1007/BF02303764

Peter F. M. Choong, Mårten Fernö, Måns Åkerman, Helena Willén, Eva Långström, Pelle Gustaeson, Thor Alvegård, Anders Rydholm, Urokinase‐plasminogen‐activator levels and prognosis in 69 soft‐tissue sarcomas International Journal of Cancer. ,vol. 69, pp. 268- 272 ,(1996) , 10.1002/(SICI)1097-0215(19960822)69:4<268::AID-IJC5>3.0.CO;2-V