Iomazenil hyperfixation in single photon emission computed tomography study of malformations of cortical development during infancy.
作者： Norimichi Higurashi , Shin-ichiro Hamano , Tomotaka Oritsu , Motoyuki Minamitani , Masayuki Sasaki
DOI: 10.1016/J.EJPN.2011.03.007
关键词:
摘要: Abstract We present 2 cases of malformations cortical development and early onset epilepsy. The first case is a patient with left hemimegalencephaly who developed focal epilepsy at the age days cluster spasms 1.5 months. After functional hemispherectomy, seizures originated from contralateral hemisphere, which had shown normal signals in preoperative magnetic resonance imaging study. second lissencephaly, caused by missense mutation doublecortin gene, West syndrome 5 In both cases, 123 I-iomazenil single photon emission computed tomography performed during infancy showed significant hyperfixation dysplastic lesions. This finding indicates immaturity affected neurons gamma-aminobutyric acidergic involvement epileptogenesis associated infancy.
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