Histology and Molecular Aspects of Central Neurocytoma

作者: Phillip A. Bonney , Lillian B. Boettcher , Richard S. Krysiak , Kar-Ming Fung , Michael E. Sughrue

DOI: 10.1016/J.NEC.2014.09.001

关键词:

摘要: Central neurocytoma (CN) is a well-differentiated tumor of neural cells occurring within the ventricles. It composed monomorphic with round, regular nuclei clear cytoplasm and must be distinguished from other cell tumors. Immunohistochemical markers CN that aid in diagnosis include synaptophysin neuronal nuclear antigen. The molecular biology these tumors becoming increasingly elucidated, particularly use microarray analyses. Several oncogenic pathways have been suggested by studies. Although progress continues to made, knowledge has yet dictate targeted therapies treating patients

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