Application of GEANT4 radiation transport toolkit to dose calculations in anthropomorphic phantoms
作者： P. Rodrigues , A. Trindade , L. Peralta , C. Alves , A. Chaves
DOI: 10.1016/J.APRADISO.2004.05.073
关键词:
摘要: In this paper, we present a novel implementation of dose calculation application, based on the GEANT4 Monte Carlo toolkit. Validation studies were performed with an homogeneous water phantom and Alderson-Rando anthropomorphic both irradiated high-energy photon beams produced by clinical linear accelerator. As input, tool requires computer tomography images for automatic codification voxel-based geometries phase-space distributions to characterize incident radiation field. Simulation results compared ionization chamber, thermoluminescent dosimetry data commercial treatment planning system calculations. phantom, overall agreement measurements within 1-2%. For simulated setups (thorax head irradiation) mean differences between TLD less than 2%. Significant semi-analytical algorithm implemented in system, found low-density regions, such as air cavities strong electronic disequilibrium.
elsevier.com
researchgate.net 
sci-hub.se 参考文章(27)
Anders Ahnesjö, Maria Mania Aspradakis, Dose calculations for external photon beams in radiotherapy Physics in Medicine and Biology. ,vol. 44, pp. R99- R155 ,(1999) , 10.1088/0031-9155/44/11/201
Thomas Bortfeld, Wolfgang Schlegel, Bernhard Rhein, Decomposition of pencil beam kernels for fast dose calculations in three-dimensional treatment planning Medical Physics. ,vol. 20, pp. 311- 318 ,(1993) , 10.1118/1.597070
Richard Taschereau, René Roy, Jean Pouliot, Relative biological effectiveness enhancement of a 125I brachytherapy seed with characteristic x rays from its constitutive materials. Medical Physics. ,vol. 29, pp. 1397- 1402 ,(2002) , 10.1118/1.1485054
Uwe Schneider, Eros Pedroni, Antony Lomax, The calibration of CT Hounsfield units for radiotherapy treatment planning Physics in Medicine and Biology. ,vol. 41, pp. 111- 124 ,(1996) , 10.1088/0031-9155/41/1/009
Rene Brun, Fons Rademakers, ROOT — An object oriented data analysis framework Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment. ,vol. 389, pp. 81- 86 ,(1997) , 10.1016/S0168-9002(97)00048-X
C. Manfredotti, U. Nastasi, R. Marchisio, C. Ongaro, G. Gervino, R. Ragona, S. Anglesio, G. Sannazzari, Monte Carlo simulation of dose distribution in electron beam radiotherapy treatment planning Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment. ,vol. 291, pp. 646- 654 ,(1990) , 10.1016/0168-9002(90)90015-X
S. Roesler, W. Heinrich, H. Schraube, Monte Carlo calculation of the radiation field at aircraft altitudes Radiation Protection Dosimetry. ,vol. 98, pp. 367- 388 ,(2002) , 10.1093/OXFORDJOURNALS.RPD.A006728
E.R Benton, E.V Benton, Space radiation dosimetry in low-Earth orbit and beyond Nuclear Instruments & Methods in Physics Research Section B-beam Interactions With Materials and Atoms. ,vol. 184, pp. 255- 294 ,(2001) , 10.1016/S0168-583X(01)00748-0
J V Siebers, P J Keall, B Libby, R Mohan, Comparison of EGS4 and MCNP4b Monte Carlo codes for generation of photon phase space distributions for a Varian 2100C. Physics in Medicine and Biology. ,vol. 44, pp. 3009- 3026 ,(1999) , 10.1088/0031-9155/44/12/311
Habib Zaidi, Relevance of accurate Monte Carlo modeling in nuclear medical imaging Medical Physics. ,vol. 26, pp. 574- 608 ,(1999) , 10.1118/1.598559