Homologous pairing capture assay and related methods and applications
作者： G. Valentin Börner , Neeraj Joshi
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摘要: A Homologous Pairing Capture Assay is described which enables detection of coalignment between homologous DNA sequences. The assay involves ligating closely positioned sequences to each other thereby generating head-to-head ligation products or inverted repeats. fragments containing an repeat are then converted into hairpin molecules. molecules can be readily separated from free Also various diagnostic applications and kits relating the assay.
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