Placental Barrier to Coagulation Factors: Its Relevance to the Coagulation Defect at Birth and to Haemorrhage in the Newborn

摘要: The placental barrier to coagulation factors was assessed by measuring their levels in maternal venous and neonatal umbilical arterial blood found be largely complete. Detailed assessments a large number of term premature neonates showed that had mild deficiency at birth. Premature more definite deficiency, which became severe with increasing prematurity. Mortality low birth weight infants associated frequently due cerebral haemorrhage. It is suggested the system should enable prophylactic treatment those deficiency.