Derivatives of 2-fluoro 3-de(2,6-dideoxy 3-C-methyl-3-0-methyl-alpha-L-ribohexopyranosyl oxy) 6-1-methyl 3-oxo erythromycin, their process of preparation and application in the synthesis of medicaments

作者: Alain Bonnet , Françoise Gambier

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摘要: 2-Fluoro-3-de((2,6-dideoxy-3-C-methyl-3-O-methyl- alpha -L-ribo-hexopyranosyl)oxy)6-O-methyl-3-oxo-erythromycin derivatives (I) and their salts are new. of formula A = OH; B + carbon in position 10 double bond; carbonate or carbamate; OZ OH, ester ether. Independent claims also included for: (1) the preparation (I); (2) (II) obtained from (I), intermediates (I: O-CO-NR; R not defined).

参考文章(4)
GEORGE GRIESGRABER, YAT SUN OR, DANIEL T. W. CHU, ANGELA M. NILIUS, PAULINE M. JOHNSON, ROBERT K. FLAMM, RODGER F. HENRY, JACOB J. PLATTNER, 3-Keto-11,12-carbazate derivatives of 6-O-methylerythromycin A synthesis and in vitro activity. The Journal of Antibiotics. ,vol. 49, pp. 465- 477 ,(1996) , 10.7164/ANTIBIOTICS.49.465
Yannick Benedetti, Constantin Agouridas, Jean-François Chantot, Alexis Denis, Erythromycin derivatives, their process of preparation and their application as medicaments ,(1993)
Jean-François Chantot, Martret Odile Le, Claude Fromentin, Constantin Agouridas, Alexis Denis, Yannick Benedetti, Erythromycin derivatives, their preparation, intermediates obtained and their application as medicaments ,(1991)
Constantin Agouridas, François Bretin, Jean-François Chantot, Erythromycin derivatives, their production and their use as medicaments ,(1996)