作者: JACK C. SABO
DOI: 10.1001/ARCHSURG.1965.01320090092021
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摘要: IN 1957 the acceleration in gain of tensile strength wounds treated with heterologous cartilage powder was established by Prudden. 1 Since that time this phenomenon has been documented many studies. 2-5 Attempts to find active ingredient(s) have unsuccessful, but substances a chemical resemblance (talcum powder, bone flour, chondroitin sulfate, chondromucoprotein, and Moss' extract) do not wound-stimulating property 6 bespeak specificity repair stimulating factor cartilage. That can be transported via blood stream shown two Prudden et al 7 showed subcutaneous implantation pellets tracheal three five days prior making incised significantly accelerated healing these wounds. In second study he found parenteral administration saline extract exerted similar effect on