Acceleration of Open Wound Healing by Cartilage

作者: JACK C. SABO

DOI: 10.1001/ARCHSURG.1965.01320090092021

关键词:

摘要: IN 1957 the acceleration in gain of tensile strength wounds treated with heterologous cartilage powder was established by Prudden. 1 Since that time this phenomenon has been documented many studies. 2-5 Attempts to find active ingredient(s) have unsuccessful, but substances a chemical resemblance (talcum powder, bone flour, chondroitin sulfate, chondromucoprotein, and Moss' extract) do not wound-stimulating property 6 bespeak specificity repair stimulating factor cartilage. That can be transported via blood stream shown two Prudden et al 7 showed subcutaneous implantation pellets tracheal three five days prior making incised significantly accelerated healing these wounds. In second study he found parenteral administration saline extract exerted similar effect on

参考文章(13)
Jorgensen O, Schmidt A, Influence of sex hormones on granulation tissue formation and on healing of linear wounds. Acta chirurgica Scandinavica. ,vol. 124, pp. 1- 10 ,(1962)
MICHAEL R. GOLDING, Cartilage Speeds Healing in Diabetic Wounds Archives of Surgery. ,vol. 87, pp. 647- 649 ,(1963) , 10.1001/ARCHSURG.1963.01310160109021
JOHN F. PRUDDEN, Subcutaneous Cartilage Pellets Archives of Surgery. ,vol. 85, pp. 245- 246 ,(1962) , 10.1001/ARCHSURG.1962.01310020075016
JOHN F. PRUDDEN, The Acceleration of Wound Healing Archives of Surgery. ,vol. 86, pp. 157- 161 ,(1963) , 10.1001/ARCHSURG.1963.01310070159020
Alexis Carrel, Alice Hartmann, CICATRIZATION OF WOUNDS : I. THE RELATION BETWEEN THE SIZE OF A WOUND AND THE RATE OF ITS CICATRIZATION. Journal of Experimental Medicine. ,vol. 24, pp. 429- 450 ,(1916) , 10.1084/JEM.24.5.429
C. A. C. Charlton, D. I. R. Higton, D. W. James, A. R. Nicol, J. O. Stewart, Wound contraction in the guinea-pig British Journal of Surgery. ,vol. 49, pp. 96- 102 ,(1961) , 10.1002/BJS.18004921322
L. Doljanski, Acceleration of Wound Healing BMJ. ,vol. 1, pp. 272- 273 ,(1947) , 10.1136/BMJ.1.4493.272-C
TAKAYUKI INOUE, The "Cartilage Effect" on Healing Wounds Archives of Surgery. ,vol. 82, pp. 432- 434 ,(1961) , 10.1001/ARCHSURG.1961.01300090102021
K Vickers, K Vickers, L Deangelo, L Deangelo, R A Jacob, R A Jacob, J C Houck, J C Houck, The inhibition of inflammation and the acceleration of tissue repair by cartilage powder Surgery. ,vol. 51, pp. 632- 638 ,(1962) , 10.5555/URI:PII:0039606062902180