Effect of sex hormones on lipid peroxidation in rat liver.
作者： Keun Huh , Uk-Seob Shin , Jong-Won Choi , Sang-Il Lee
DOI: 10.1007/BF02974233
关键词:
摘要: The role of sex hormones in hepatic lipid peroxidation, and aldehyde oxidase xanthine activities were investigated using rat liver homogenates. It was observed that male had a significantly greater content malondialdehyde than female. Among the tested, estradiol, one female hormones, markeldy inhibited formation peroxides tissuesin vitro. Especially, inhibitory effect estradiol appeared more remarkably Fe2-induced peroxidation. activity decreased about 15% by 106M whereas, almost completely disappeared at same concentration estradiol. implies differences peroxidation is attributed to suppression free radical generating system
springer.com
sci-hub.se 参考文章(23)
J M McCord, The superoxide free radical: its biochemistry and pathophysiology. Surgery. ,vol. 94, pp. 412- 414 ,(1983)
Comporti M, Lipid peroxidation and cellular damage in toxic liver injury. Laboratory Investigation. ,vol. 53, pp. 599- 623 ,(1985)
D A Parks, M E Höllwarth, D N Granger, Ischemia-reperfusion injury: role of oxygen-derived free radicals. Acta Physiologica Scandinavica. ,vol. 548, pp. 47- 63 ,(1986)
Umberto Branzoli, Vincent Massey, Preparation of aldehyde oxidase in its native and deflavo forms. Comparison of spectroscopic and catalytic properties. Journal of Biological Chemistry. ,vol. 249, pp. 4339- 4345 ,(1974) , 10.1016/S0021-9258(19)42425-3
Esteban Mezey, Savitri Sharma, Lynda Rennie, James J. Potter, Sex differences in gastric alcohol dehydrogenase activity in Sprague-Dawley rats. Gastroenterology. ,vol. 103, pp. 1804- 1810 ,(1992) , 10.1016/0016-5085(92)91438-A
E della Corte, F Stirpe, E Lorenzoni, The Regulation of Rat Liver Xanthine Oxidase CONVERSION IN VITRO OF THE ENZYME ACTIVITY FROM DEHYDROGENASE (TYPE D) TO OXIDASE (TYPE O) Journal of Biological Chemistry. ,vol. 244, pp. 3855- 3863 ,(1969) , 10.1016/S0021-9258(17)36428-1
D J Hearse, A S Manning, D M Yellon, J M Downey, Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion? Acta Physiologica Scandinavica. ,vol. 548, pp. 65- 78 ,(1986)
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
W. I. M. Holman, C. Wiegand, The chemical conversion of nicotinic acid and nicotinamide to derivatives of N-methyl-2-pyridone by methylation and oxidation. Biochemical Journal. ,vol. 43, pp. 423- 426 ,(1948) , 10.1042/BJ0430423
Rafat S. Hashmi, Abdul Moid Siddiqui, Manvendra S. Kachole, Sitaram S. Pawar, Alterations in Hepatic Microsomal Mixed-Function Oxidase System during Different Levels of Food Restriction in Adult Male and Female Rats The Journal of Nutrition. ,vol. 116, pp. 682- 688 ,(1986) , 10.1093/JN/116.4.682