Population pharmacokinetic and pharmacodynamic analysis of ribavirin in patients with chronic hepatitis C.
作者： J. Frank Jen , Paul Glue , Samir Gupta , Demetris Zambas , Gerald Hajian
DOI: 10.1097/00007691-200010000-00010
关键词:
摘要: Summary:The population pharmacokinetics of ribavirin were assessed in patients with chronic hepatitis C virus (HCV) infection treated interferon α-2b and four clinical efficacy studies. The authors collected 3450 serum concentrations from 1105 at different treatm
lww.com 
sci-hub.se 参考文章(19)
Donald W. Cockcroft, Henry Gault, Prediction of Creatinine Clearance from Serum Creatinine Nephron. ,vol. 16, pp. 31- 41 ,(1976) , 10.1159/000180580
Adrian M. Di Bisceglie, Ribavirin as Therapy for Chronic Hepatitis C Annals of Internal Medicine. ,vol. 123, pp. 897- 903 ,(1995) , 10.7326/0003-4819-123-12-199512150-00001
Salim Khakoo, Paul Glue, Leonie Grellier, Beverley Wells, Allan Bell, Clive Dash, Iain Murray-Lyon, David Lypnyj, Brian Flannery, Karen Walters, Geoffrey M Dusheiko, Ribavirin and interferon alfa-2b in chronic hepatitis C: assessment of possible pharmacokinetic and pharmacodynamic interactions British Journal of Clinical Pharmacology. ,vol. 46, pp. 563- 570 ,(1998) , 10.1046/J.1365-2125.1998.00836.X
Adrian M di Bisceglie, Michiko Shindo, Tse-Ling Fong, Michael W Fried, Mark G Swain, Nora V Bergasa, Constantine A Axiotis, Jeanne G Waggoner, Yoon Park, Jay H Hoofnagle, None, A pilot study of ribavirin therapy for chronic hepatitis C. Hepatology. ,vol. 16, pp. 649- 654 ,(1992) , 10.1002/HEP.1840160307
J. A. Garson, K. Whitby, R. Deaville, S. Brillanti, M. Foli, C. Masci, M. Miglioli, L. Barbara, Analysis of clinical and virological factors associated with response to alpha interferon therapy in chronic hepatitis C. Journal of Medical Virology. ,vol. 45, pp. 348- 353 ,(1995) , 10.1002/JMV.1890450320
Toshio Suzuki, Eiji Tanaka, Akihiro Matsumoto, Akihiko Urushihara, Takeshi Sodeyama, Usefulness of simple assays for serum concentration of hepatitis C virus RNA and HCV genotype in predicting the response of patients with chronic hepatitis C to interferon α2a therapy Journal of Medical Virology. ,vol. 46, pp. 162- 168 ,(1995) , 10.1002/JMV.1890460215
NORIO HORIIKE, TOSHIKAZU MASUMOTO, KIMIO NAKANISHI, KOJIRO MICHITAKA, KIYOTAKA KUROSE, IZUMI OHKURA, MORIKAZU ONJI, Interferon therapy for patients more than 60 years of age with chronic hepatitis C Journal of Gastroenterology and Hepatology. ,vol. 10, pp. 246- 249 ,(1995) , 10.1111/J.1440-1746.1995.TB01088.X
J.Y.N Lau, G.L Davis, J Kniffen, K.-P Qian, M.S Urdea, C.S Chan, P.D Neuwald, J.C Wilber, M Mizokami, Significance of serum hepatitis C virus RNA levels in chronic hepatitis C The Lancet. ,vol. 341, pp. 1501- 1504 ,(1993) , 10.1016/0140-6736(93)90635-T
Kentaro Yoshioka, Shinichi Kakumu, Takaji Wakita, Tetsuya Ishikawa, Yuji Itoh, Masahiro Takayanagi, Yasuyuki Higashi, Motohiro Shibata, Tsuneo Morishima, Detection of hepatitis C virus by polymerase chain reaction and response to interferon‐α therapy: Relationship to genotypes of hepatitis C virus Hepatology. ,vol. 16, pp. 293- 299 ,(1992) , 10.1002/HEP.1840160203
Robert W. Sidwell, Roland K. Robins, Ira W. Hillyard, Ribavirin: An antiviral agent Pharmacology & Therapeutics. ,vol. 6, pp. 123- 146 ,(1979) , 10.1016/0163-7258(79)90058-5