Cortical neuronal function during ischemia. Effects of occlusion of one middle cerebral artery on single-unit activity in cats.
作者： Wolf-Dieter Heiss
DOI: 10.1001/ARCHNEUR.1976.00500120017003
关键词:
摘要: • To assess the effects of ischemia on neuronal function, action potentials 261 individual cortical neurons were recorded extracellularly and related to regional cerebral blood flow (CBF) measured by hydrogen clearance in 19 cats, seven which had left middle artery occluded during a recording. The onset could be associated with transient increases activity, including "seizure discharges," as well cessation activity. No activity was noted at CBF less than 0.18 ml/gm/min; higher (but ischemic) values for CBF, abnormal patterns frequently recorded. One neuron recovered function after association an increase indicating potential restoration ischemic effective therapeutic measures.
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