Living-related donor iobectomy for bilateral lobar transplantation in patients with cystic fibrosis

摘要: Abstract Donor lobectomy has been performed in 14 patients enabling 7 recipients with cystic fibrosis to undergo bilateral living-related lobar pulmonary transplantation. Donors included 11 parents, 2 brothers, and 1 uncle. mean age was 43 years (range 24 55 years). Their height weight 170 cm (range, 169 180 cm) 72.4 kg 90 kg), respectively, compared 161 140 175 42.4 27 the recipient group. evaluation consisted of a history physical examination, chest roentgenogram computed tomographic scan, spirometry arterial blood gas measurement, echocardiography, perfusion scanning. From each pair donors, one selected for right lower other left lobec tomy. Standard techniques were modified facilitate implantation optimize preservation donor lobes. On side, middle lobe removed discarded first three donors provide an adequate cuff artery bronchus implantation. With increased experience, this proved not be necessary. There have no deaths long-term complications Prolonged postoperative air leaks occurred 3 who underwent lobectomies. All able resume their previous lifestyles. Living-related provides alternative cadaveric organs select need