1,3,4-thiadiazole and its derivatives: a review on recent progress in biological activities.

作者: Abhishek Kumar Jain , Simant Sharma , Ankur Vaidya , Veerasamy Ravichandran , Ram Kishore Agrawal

DOI: 10.1111/CBDD.12125

关键词:

摘要: The 1,3,4-thiadiazole nucleus is one of the most important and well-known heterocyclic nuclei, which a common integral feature variety natural products medicinal agents. Thiadiazole present as core structural component in an array drug categories such antimicrobial, anti-inflammatory, analgesic, antiepileptic, antiviral, antineoplastic, antitubercular broad potent activity thiadiazole their derivatives has established them pharmacologically significant scaffolds. In this study, attempt been made with recent research findings on nucleus, to review modifications different for various pharmacological activities.

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