What Have We Learned from the SWORD Trial? Can Potassium Channel Blockers Reduce Sudden Cardiac Death?

作者: P. J. Schwartz

DOI: 10.1007/978-88-470-2223-2_7

关键词:

摘要: On November 1, 1994, the SWORD (Survival With Oral D-sotalol) trial was terminated by Steering Committee because of an excess mortality among patients randomized to d-sotalol. Five years after early termination Cardiac Arrhythmia Suppression Trial (CAST) for similar reasons, this event has caused further concern in field cardiac arrhythmias and electrophysiology is raising questions about availability drugs that may reduce sudden death also rationale events precede initiation large-scale clinical trials.

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