The Predictive Role of Hyposmia in Alzheimer's Disease

摘要: Loss of olfactory function starts at 60 years and become significantly worse after 70. In many cases disorders may be a consequence disease. Different types deficit revealed by smell evaluation. Anosmia is defined as inability to perceive all odors (total) or some (partial). Hyposmia microsmia decreased sensitivity odors. Dysosmia distorted percpeption. Olfactory agnosia failure identify in presence normal detection discrimination. allucinations are named phantosmias. Many common diseases compromise the sense smell, permanently temporaneally. The range causing varies from cold neurodegenerative diseases. Most causes loss local nasal (allergic rhinitis, polyposis, sinus disease), head trauma, viral bacterial infections upper airways. Some like Alzheimer's disease (AD) various forms Parkinson’s (PD) accompanied, even their earliest stages, disorders. Dementia American Academy Neurology progressive permanent decline cognitive affects nearly 15% people who live up 65 35% those reach age 85. Disease International (ADI) Alzheimer World Report published 2010 provides that an aging population with dementia most form AD which currently estimated affect 35,6 million will double 20 66 2030 higher concentration poor countries leading enormous social costs. research on now oriented early diagnosis essential before development irreversible typical changes due AD. patients, reduced capacity for detection, discrimination identification usually found confirmed several studies (Mesholam et al., 1998; Hawkes, 2003; Kovacs, 2004; Albers 2006; Westervelt 2007). this chapter we present review predictive role hyposmia patients.