Effects of Mild and Severe Vitamin B1 Deficiencies on the Meiotic Maturation of Mice Oocytes
作者： Ai Tsuji , Toshinobu Nakamura , Katsumi Shibata
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摘要: We investigated the effects of vitamin B1 deficiency on meiosis maturation oocytes. Female Crl:CD1 (ICR) mice were fed a 20% casein diet (control group) or B1–free (test group). The concentration in ovary was approximately 30% lower test group than control group. Oocyte not affected by when accompanied body weight loss. On contrary, frequency abnormal oocyte increased loss (referred to as severe deficiency; oocyte, 13.8% vs 43.7%, P = .0071). oocytes decreased refeeding B1–containing (13.9% 22.9%, = .503). These results suggest that inhibited meiotic but did damage immature
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