Creatine Supplementation Enhances Isometric Strength and Body Composition Improvements Following Strength Exercise Training in Older Adults

作者: A. Brose , G. Parise , M. A. Tarnopolsky

DOI: 10.1093/GERONA/58.1.B11

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摘要: We sought to determine whether creatine monohydrate (CrM) supplementation would enhance the increases in strength and fat-free mass that develop during resistance exercise training in older adults. Twenty-eight healthy men and women over the age of 65 years participated in a whole-body resistance exercise program 3 days per week for 14 weeks. The study participants were randomly allocated, in a double-blind fashion, to receive either CrM (5 g/d+ 2 g of dextrose; n= 14) or placebo (7 g of dextrose; n= 14). The primary outcome …

参考文章(62)
Lohman Tg, Skinfolds and body density and their relation to body fatness: a review. Human Biology. ,vol. 53, pp. 181- 225 ,(1981)
E. Joan Bassey, Maria A. Fiatarone, Evelyn F. O'neill, Margaret Kelly, William J. Evans, Lewis A. Lipsitz, Leg extensor power and functional performance in very old men and women. Clinical Science. ,vol. 82, pp. 321- 327 ,(1992) , 10.1042/CS0820321
Roger C. Harris, Karin Söderlund, Eric Hultman, Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation Clinical Science. ,vol. 83, pp. 367- 374 ,(1992) , 10.1042/CS0830367
G. Parise, S. Mihic, D. MacLennan, K. E. Yarasheski, M. A. Tarnopolsky, Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis Journal of Applied Physiology. ,vol. 91, pp. 1041- 1047 ,(2001) , 10.1152/JAPPL.2001.91.3.1041
T. J. Doherty, A. A. Vandervoort, A. W. Taylor, W. F. Brown, Effects of motor unit losses on strength in older men and women Journal of Applied Physiology. ,vol. 74, pp. 868- 874 ,(1993) , 10.1152/JAPPL.1993.74.2.868
MATTHIAS KAMBER, MARKUS KOSTER, ROLAND KREIS, GIANNI WALKER, CHRIS BOESCH, HANS HOPPELER, Creatine supplementation--part I: performance, clinical chemistry, and muscle volume. Medicine and Science in Sports and Exercise. ,vol. 31, pp. 1763- 1769 ,(1999) , 10.1097/00005768-199912000-00011
Molly T Kibenge, Catherine B Chan, Interactions between effects of adrenalectomy and diet on insulin secretion in fa/fa Zucker rats. Canadian Journal of Physiology and Pharmacology. ,vol. 79, pp. 1- 7 ,(2001) , 10.1139/Y00-106
M. Tarnopolsky, J. Martin, Creatine monohydrate increases strength in patients with neuromuscular disease Neurology. ,vol. 52, pp. 854- 854 ,(1999) , 10.1212/WNL.52.4.854
Dawn A. Skelton, Archie Young, Carolyn A. Greig, Katie E. Malbut, Effects of Resistance Training on Strength, Power, and Selected Functional Abilities of Women Aged 75 and Older Journal of the American Geriatrics Society. ,vol. 43, pp. 1081- 1087 ,(1995) , 10.1111/J.1532-5415.1995.TB07004.X